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Loss of Response

This IBD clinical care pathway is a guideline for healthcare professionals to achieve and maintain remission with advanced therapy, especially for adult IBD patients who are on newer biologics and small molecules.

 

Use the Pathway

Download the PDF

 

Dr. Jesse Siffledeen (University of Alberta & Covenant Health/Grey Nuns Hospital Edmonton) and Dr. Vivian Huang (University of Toronto & Mount Sinai Hospital) are the leads for this clinical care pathway, including regular review and maintenance.

Last reviewed and updated in June 2025.

Disclaimer
Clinical care pathways are not a substitute for the personalized judgement and care of a trained healthcare professional. 

 

  • Canada has among the highest incidence rates of Crohn's and colitis in the world.
  • 1 in 140 Canadians lives with Crohn’s or colitis.
  • Families new to Canada are developing these diseases for the first time.
  • Incidence of Crohn’s in Canadian kids under 10 has doubled since 1995.
  • People are most commonly diagnosed before age 30.

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