The Genetic, Environmental, Microbial (GEM) Project

Watch the video to learn about recent advancements of The GEM Project. This project is a global research study that looks to uncover possible triggers of Crohn’s disease. The more we know about the possible causes of Crohn’s, the closer we get not only to a cure, but also to the ability to prevent the disease from taking hold in the first place.



Dr. Kenneth Croitoru (MDCM, FRCP) is a full Professor of Medicine and Clinician Scientist at the University of Toronto and Mount Sinai Hospital. ​He is the Project Leader of, the GEM Project, out of the IBD Research Group and Zane Cohen Center at Mount Sinai Hospital. This study has had over $15 million in funding from Crohn's Colitis Canada, CIHR and the Helmsley Charitable Trust.

Dr. Croitoru completed medical school at McGill University in 1981 and then trained in internal medicine and gastroenterology from 1982-1986. He went on to do post-doctoral training as an MRC Research Fellow in Mucosal Immunology with Dr. John Bienenstock at McMaster University.

Dr. Croitoru held an Ontario Ministry of Health Career Scientist award for 10 years and was one of the first recipients of a 5-year CCC IBD Research Scientist Award. His research focuses on investigating the fundamental mechanisms of intestinal inflammation. 

  • Canada has among the highest incidence rates of Crohn's and colitis in the world.
  • 1 in 140 Canadians lives with Crohn’s or colitis.
  • Families new to Canada are developing these diseases for the first time.
  • Incidence of Crohn’s in Canadian kids under 10 has doubled since 1995.
  • People are most commonly diagnosed before age 30.

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