Nutritional Optimization

Nutrition optimization in malnourished patients with Crohn’s disease is associated with beneficial gut microbiome changes

From Dr Maitreyi Raman, Clinical Associate Professor, University of Calgary

Patients with Crohn’s disease are likely to benefit from nutritional counseling at all stages of disease, including remission. Nutritional deficiencies occur in Crohn’s disease with high frequency. The gut flora may be affected through dietary deficiencies leading to flares of the disease. As such, we plan to investigate the impact of a nutritional strategy in patients with Crohn’s disease. The study goals are to investigate the impact of diet on the gut flora.

Recently I have received a grant from the Crohn’s and Colitis Foundation of America to study the above mentioned research objective. If you are an eligible participant**, I would like to invite you to participate in the study. If you are a physician, I would like you to refer your eligible patients to this study. To enroll or to provide information of eligible patient, please contact study coordinator - Salim Ahmed, Phone: 403-592-5231 or E-mail:

Participation in this study is completely voluntary but invaluable to us to provide better treatments in the future for patients with Crohn’s disease. If your diet requires optimization, you will have the opportunity to meet with a registered dietitian for nutritional counseling. All information collected during this study, including your personal health information, will be kept confidential and will not be released to anyone outside the study. Parking costs for visits to the research site will be covered.

**Inclusion criteria: Crohn’s disease patient, at least 18 years of age, normal colonoscopy within 6 months or willingness to undergo colonoscopy to assess eligibility.
**Exclusion criteria: Any antibiotic, laxative or steroid use within 3 months, more than one bowel surgery, use of daily nutritional, micronutrient, vitamin supplement.

Dr Maitreyi Raman, MD, MSc, FRCPC
Clinical Associate Professor, University of Calgary
Division of Gastroenterology and Hepatology

  • Canada has among the highest incidence rates of Crohn's and colitis in the world.
  • 1 in 140 Canadians lives with Crohn’s or colitis.
  • Families new to Canada are developing these diseases for the first time.
  • Incidence of Crohn’s in Canadian kids under 10 has doubled since 1995.
  • People are most commonly diagnosed before age 30.

Other Areas of Interest